DominoEffect

This is the development version of DominoEffect; for the stable release version, see DominoEffect.

Identification and Annotation of Protein Hotspot Residues


Bioconductor version: Development (3.21)

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Author: Marija Buljan and Peter Blattmann

Maintainer: Marija Buljan <marija.buljan.2 at gmail.com>, Peter Blattmann <peter_blattmann at bluewin.ch>

Citation (from within R, enter citation("DominoEffect")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("DominoEffect")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DominoEffect")
Vignette for DominoEffect package HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Alignment, Proteomics, SequenceMatching, Software, SomaticMutation
Version 1.27.0
In Bioconductor since BioC 3.7 (R-3.5) (6.5 years)
License GPL (>= 3)
Depends R (>= 3.5)
Imports biomaRt, data.table, utils, stats, Biostrings, pwalign, SummarizedExperiment, VariantAnnotation, AnnotationDbi, GenomeInfoDb, IRanges, GenomicRanges, methods
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Suggests knitr, testthat, rmarkdown
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DominoEffect_1.27.0.tar.gz
Windows Binary (x86_64) DominoEffect_1.27.0.zip
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/DominoEffect
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DominoEffect
Bioc Package Browser https://code.bioconductor.org/browse/DominoEffect/
Package Short Url https://bioconductor.org/packages/DominoEffect/
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