MotifPeeker

This is the development version of MotifPeeker; to use it, please install the devel version of Bioconductor.

Benchmarking Epigenomic Profiling Methods Using Motif Enrichment


Bioconductor version: Development (3.21)

MotifPeeker is used to compare and analyse datasets from epigenomic profiling methods with motif enrichment as the key benchmark. The package outputs an HTML report consisting of three sections: (1. General Metrics) Overview of peaks-related general metrics for the datasets (FRiP scores, peak widths and motif-summit distances). (2. Known Motif Enrichment Analysis) Statistics for the frequency of user-provided motifs enriched in the datasets. (3. De-Novo Motif Enrichment Analysis) Statistics for the frequency of de-novo discovered motifs enriched in the datasets and compared with known motifs.

Author: Hiranyamaya Dash [cre, aut] (ORCID: ), Thomas Roberts [aut] (ORCID: ), Maria Weinert [aut] (ORCID: ), Nathan Skene [aut] (ORCID: )

Maintainer: Hiranyamaya Dash <hdash.work at gmail.com>

Citation (from within R, enter citation("MotifPeeker")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("MotifPeeker")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MotifPeeker")
MotifPeeker HTML R Script
troubleshooting HTML R Script
Reference Manual PDF
NEWS Text
INSTALL Text

Details

biocViews Alignment, ChIPSeq, Epigenetics, FunctionalGenomics, Genetics, MotifDiscovery, MultipleComparison, QualityControl, SequenceMatching, Software
Version 0.99.12
In Bioconductor since BioC 3.21 (R-4.5)
License GPL (>= 3)
Depends R (>= 4.4.0)
Imports BiocFileCache, BiocParallel, DT, ggplot2, plotly, universalmotif, GenomicRanges, IRanges, rtracklayer, tools, htmltools, rmarkdown, viridis, SummarizedExperiment, htmlwidgets, Rsamtools, GenomicAlignments, GenomeInfoDb, Biostrings, BSgenome, memes, S4Vectors, dplyr, purrr, tidyr, heatmaply, stats, utils
System Requirements MEME Suite (v5.3.3 or above)
URL https://github.com/neurogenomics/MotifPeeker
Bug Reports https://github.com/neurogenomics/MotifPeeker/issues
See More
Suggests BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.UCSC.hg38, downloadthis, knitr, markdown, methods, remotes, rworkflows, testthat (>= 3.0.0), withr, emoji, curl, jsonlite
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MotifPeeker_0.99.12.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/MotifPeeker
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MotifPeeker
Bioc Package Browser https://code.bioconductor.org/browse/MotifPeeker/
Package Short Url https://bioconductor.org/packages/MotifPeeker/
Package Downloads Report Download Stats