geva

Gene Expression Variation Analysis (GEVA)


Bioconductor version: Release (3.20)

Statistic methods to evaluate variations of differential expression (DE) between multiple biological conditions. It takes into account the fold-changes and p-values from previous differential expression (DE) results that use large-scale data (*e.g.*, microarray and RNA-seq) and evaluates which genes would react in response to the distinct experiments. This evaluation involves an unique pipeline of statistical methods, including weighted summarization, quantile detection, cluster analysis, and ANOVA tests, in order to classify a subset of relevant genes whose DE is similar or dependent to certain biological factors.

Author: Itamar José Guimarães Nunes [aut, cre] , Murilo Zanini David [ctb], Bruno César Feltes [ctb] , Marcio Dorn [ctb]

Maintainer: Itamar José Guimarães Nunes <nunesijg at gmail.com>

Citation (from within R, enter citation("geva")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("geva")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("geva")
GEVA PDF R Script
Reference Manual PDF
NEWS Text

Details

biocViews Classification, DifferentialExpression, GeneExpression, Microarray, MultipleComparison, RNASeq, Software, SystemsBiology, Transcriptomics
Version 1.14.0
In Bioconductor since BioC 3.13 (R-4.1) (3.5 years)
License LGPL-3
Depends R (>= 4.1)
Imports grDevices, graphics, methods, stats, utils, dbscan, fastcluster, matrixStats
System Requirements
URL https://github.com/sbcblab/geva
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Suggests devtools, knitr, rmarkdown, roxygen2, limma, topGO, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package geva_1.14.0.tar.gz
Windows Binary (x86_64) geva_1.14.0.zip
macOS Binary (x86_64) geva_1.14.0.tgz
macOS Binary (arm64) geva_1.14.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/geva
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/geva
Bioc Package Browser https://code.bioconductor.org/browse/geva/
Package Short Url https://bioconductor.org/packages/geva/
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